Assuntos
Tatus/genética , Sistema do Grupo Sanguíneo Duffy/genética , Eritrócitos , Fenótipo , Animais , Tatus/sangue , Tatus/classificação , Feminino , MasculinoAssuntos
Animais , Masculino , Feminino , Tatus/genética , Sistema do Grupo Sanguíneo Duffy/genética , Eritrócitos , Fenótipo , Tatus/sangue , Tatus/classificaçãoRESUMO
A study of leishmanin skin test reactors was carried out in 1997 and 1998 in an endemic region in southeast Spain, to estimate the magnitude of and the factors related to subclinical Leishmania infantum infection. In the main focus of leishmaniasis in the region, 11.5% of the children and 52.8% of the adults reacted to the skin test. Among the adults, the response was significantly greater for males and for those who had resided in the area for > or = 15 years. In the whole region, 3.7% 14-year-old students reacted to the skin test, with no gender differences. The main factors related to a positive skin test result were having a parent or sibling recovered from leishmaniasis (relative risk = 14) and living in the rural periphery of the region as opposed to the metropolitan area (relative risk = 4). These results indicate a high frequency of subclinical leishmaniasis in the region. We postulate that the decline in childhood visceral leishmaniasis in southern Europe in the second half of the 20th century is related to social changes, which gave rise to a less frequent exposure at a young age as well as a lowered susceptibility to disease through nutritional and immune improvements.
Assuntos
Leishmania infantum/isolamento & purificação , Leishmaniose Cutânea/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Animais , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de Risco , Distribuição por Sexo , Pele/parasitologia , Testes Cutâneos/métodos , Espanha/epidemiologiaRESUMO
The case is reported of a 20-month-old girl admitted to our centre for group B streptococcal endocarditis who died of complete atrioventricular block after a week of treatment. There was no history pointing to the presence of a heart disorder. Necropsy disclosed the surprising existence of a vast rheumatic carditis involving essentially the aortic and mitral valves, with bacterial superinfection of the former. The double rheumatic and infectious lesion in such a young patient with infective pseudo-aneurysms of the sinuses of Valsalva makes this an exceptional case.
Assuntos
Aneurisma da Aorta Torácica/patologia , Endocardite Bacteriana/patologia , Cardiopatia Reumática/patologia , Infecções Estreptocócicas/patologia , Streptococcus agalactiae , Aneurisma da Aorta Torácica/complicações , Endocardite Bacteriana/complicações , Feminino , Bloqueio Cardíaco/etiologia , Humanos , Lactente , Cardiopatia Reumática/complicações , Seio Aórtico , Infecções Estreptocócicas/complicaçõesRESUMO
A case of cutaneous and renal geotrichosis in a giant tortoise, Geochelone elephantopus, at the Zoological Park of Barcelona is reported. Fungal hyphae and spores were seen in skin and kidney. Culture of these tissues yielded Geotrichum candidum. This fungus was isolated from the faeces of 5 other giant tortoises that were housed with the dead animal and from specimens of corn hydroponic culture which is part of their diet. Arthrospore suspensions of the 2 strains isolated from the dead animal's skin and kidney were experimentally inoculated into mice and turtles (Testudo horsfiedi) in order to determine the pathogenicity of G. candidum for animal tissues. Our results confirm its low pathogenicity.
